Inhibitors of the Wnt signaling pathway having the structure of Formula I are disclosed along with their pharmaceutical salts. Also disclosed is the use of compounds of formula I in inhibiting or modulating the Wnt signaling pathway. The compounds of formula I can treat diseases caused by abnormal activation of the Wnt signaling pathway. [Selection] Figure 1式Iの構造を有するWntシグナル経路の阻害剤が、それらの薬学的塩と共に開示される。Wntシグナル経路の阻害または調節における式Iの化合物の用途もまた開示される。式Iの化合物はWntシグナル経路の異常活性化によって引き起こされる疾患を治療し得る。【選択図】図1