Kun Liu,Shawn J. Stachel,Craig A. Coburn,Thomas G. Steele,Richard Soll,Hao Wu,Xuanjin Peng,Yaxian Cai,Xiaoxiang Du,Jian Li
申请号：
US13201570
公开号：
US08865701B2
申请日:
2010.02.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention is directed to spiropyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimers disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
