YUFENG WANG,WU YANG,MICHAEL J. ORWAT,TIANAN FANG,WILLIAM R. EWING,YEHENG ZHU,ANDREW K. DILGER,RUTH R.WEXLER,JAMES R. CORTE,INDAWATI DE LUCCA,KUMAR BALASHANMUGA PABBISETTY,DONALD J. P. PINTO,LEON M. II
申请号：
PT15705860
公开号：
PT3099687T
申请日:
2015.01.30
申请国别(地区):
PT
年份:
2018
代理人:
摘要：
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
