Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet);Institut National de la Santé et de la Recherche Médicale (INSERM);Universidad Católica de Córdoba (UCC);Assistance Publique Hôpita
发明人:
申请号：
EP13760112.6
公开号：
EP2869829B1
申请日:
2013.07.05
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The invention provides compositions for oral delivery and methods of treatment using VSP carriers, such as Giardia sp. variable surface proteins (VSP), to deliver therapeutic agents. VSP drug carriers can be combined with bioactive peptides, e.g. , insulin, glucagon, or hGH, and be administered orally or mucosally. VSP carriers are resistant to acidic pHs and to proteolytic degradation and protect therapeutic agents from degradation in the gastrointestinal tract.
