igfbp3 / tmem219 axis inhibitor, pharmaceutical composition for use in the treatment and / or prevention of diabetes, method for identifying an individual at risk for developing type 1 and / or type 2 diabetes or for monitoring the response to therapeutic treatment in an individual and kit
The present invention relates to the function of the igfbp3 / tmem219 axis in the onset of diabetes and the related use of the igfbp3 / tmem219 axis inhibitors for the treatment and / or prevention of diabetes. The invention also relates to a method for identifying an individual at risk of developing type 1 and / or type 2 diabetes and related kit.a presente invenção se refere à função do eixo igfbp3/tmem219 no início do diabetes e o uso relacionado dos inibidores de eixo igfbp3/tmem219 para o tratamento e/ou prevenção de diabetes. a invenção também se refere a um método para identificar um indivíduo em risco de desenvolver diabetes tipo 1 e/ou tipo 2 e kit relacionado.