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amide derivatives
专利权人:
ASTELLAS PHARMA INC.
发明人:
KONTANI, TORU C/O ASTELLAS PHARMA INC.,MIYATA, JUNJI C/O ASTELLAS PHARMA INC.,HAMAGUCHI, WATARU C/O ASTELLAS PHARMA INC.,KAWANO, TOMOAKI C/O ASTELLAS PHARMA INC.,KAMIKAWA, AKIO C/O ASTELLAS PHARMA INC
申请号:
DK04748296
公开号:
DK1652843T3
申请日:
2004.08.05
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
There is provided a pharmaceutical drug, particularly a novel compound useful for prophylaxis or a therapeutic treatment of various diseases involving infections with viruses of the herpesvirus family, specifically various herpesvirus infections such as varicella (chicken pox) via varicella zoster virus, varicella zoster via recurrent infection with latent varicella zoster virus, herpes labialis and herpes encephalitis via HSV-1 and genital herpes via HSV-2 infection. An N-{2-[(4-substituted phenyl)amino]-2-oxoethyl}tetrahydro-2H-thiopyran-4-carboxamide derivative, of which phenyl group is substituted at position 4 with a specific 5- or 6-membered heteroaryl group, and a salt thereof have an effective anti-virus activity, and the oral administration thereof at a low dose enabled the therapeutic treatment of the above diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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