Provided is a pressurized vibration applying apparatus capable of improving a drug delivery rate by applying pressurized vibration to a medicine airflow in consideration of a patient's respiratory state. The apparatus includes a main body for generating a gas flow, a gas supply hose for supplying a gas flow from the main body into the nasal cavity, and a nosepiece attached to a distal end of the gas supply hose. An opening 6 that opens at a boundary with the proximal end 4a of the nebulizer nosepiece 4, a pressure line 7 having the opening 6 as a downstream end, and an upstream end of the pressure line 7 connected to the upstream of the pressure line 7 to apply a pressure , A valve device 9 provided in the middle of the pressure line 7 and between the pressure pump 8 and the opening 6, and controlling the opening and closing of the valve device 9, 8 is provided with a control unit 10 for converting the pressure into a desired pressurized vibration waveform and a temperature sensor 11 for measuring parameters reflecting the expiration and inspiration of the patient. [Selection diagram] Fig. 1【課題】患者の呼吸状態を考慮して薬剤気流に加圧振動を印加することで薬剤送達率を向上できる加圧振動付加装置を提供する。【解決手段】薬剤気流を発生させる本体２と、本体２から鼻腔内に薬剤気流を送気するための送気ホース３と、送気ホース３の遠位端に装着されるノーズピース４を備えるネブライザーノーズピース４の近位端４ａとの境界部に開口する開口部６と、開口部６を下流端とする加圧ライン７と、加圧ライン７の上流端に接続され、薬剤気流に圧力を印加する加圧ポンプ８と、加圧ライン７の途中であって、加圧ポンプ８と開口部６の間に設けられる弁装置９と、弁装置９の開閉を制御して、加圧ポンプ８の圧力を所望の加圧振動波形に変換する制御部１０と、患者の呼気及び吸気を反映するパラメータを計測する温度センサー１１を備える。【選択図】図１
