Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)

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专利权人:

Novo Nordisk A/S

发明人:

Vibeke Westphal Stennicke,Christine Brender Read,Susanne Nedergaard Grell,Charlotte Wiberg,Rune Salbo,Anette Henriksen,Soeren Padkjaer

申请号：

US13690748

公开号：

US09000127B2

申请日:

2012.11.30

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The invention relates to antibodies that are capable of specifically binding TREM-1 and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease, such as rheumatoid arthritis and inflammatory bowel disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/