STEINEGER, HILDE HERMANSEN,FRASER, DAVID ALAN,SKJAERET, TORE
申请号：
CA3084728
公开号：
CA3084728A1
申请日:
2018.12.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure provides a compound for use in therapeutic and/or prophylactic treatment of non-alcoholic steatohepatitis (NASH) and/or alcoholic steatohepatitis (ASH). The compound for use according to the invention, is an unsaturated fatty acid with an oxygen incorporated in the ß-position, and further comprising an a-substituent. More particularly, the invention provides a compound for use in treatment of NASH and/or ASH, and a method using this, wherein the compound is of Formula (II), wherein R1, R2, R3, X, and Y are as defined in the specification； and wherein this compound may be administered alone or in combination with an additional active agent.
