Laman Lynn Alani,Jim H. Kou,Shook-Fong Chin,Guangbin Ding,Natasha G. Masand
申请号:
US13519093
公开号:
US20130064896A1
申请日:
2010.12.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The disclosure provides multiparticulate systems that give release of active agents with a narrow window of absorption such that there is bioavailability to a patient. The disclosure provides a composition comprising microparticulates comprising a swellable hydrophilic polymer and an active agent, wherein the swellable hydrophilic polymer is substantially non-crosslinked intramolecularly, and the size of the microparticulates is about 500 μm or less.