Ester G. Fernandez-Salas;Kei Roger Aoki;Joseph Francis;Marcella A. Gilmore;Shengwen Li;Lance E. Steward
发明人:
Lance E. Steward,Joseph Francis,Ester G. Fernandez-Salas,Marcella A. Gilmore,Shengwen Li,Kei Roger Aoki
申请号:
US11776043
公开号:
US08518417B1
申请日:
2007.07.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain, a translocation facilitating domain and an enhanced targeting domain; polynucleotide molecules encoding such modified Clostridial toxins; and method of producing such modified Clostridial toxins.