Alexandre J. Buckmelter,Bainian Feng,Brad Newhouse,David Moreno,Ellen R. Laird,Hongqi Tian,Janet Gunzner,Jason de Meese,Jeongbeob Seo,Joachim Rudolph,Jonas Grina,Joshua D. Hansen,Kateri A. Ahrendt,Kim
申请号:
BRPI0908268
公开号:
BRPI0908268A2
申请日:
2009.02.27
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.