Nationwide Childrens Hospital;Nationwide Children's Hospital; Inc.
发明人:
Gail E. Besner
申请号：
US13670005
公开号：
US20130130984A1
申请日:
2012.11.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides for methods of protecting neurons within the enteric nervous system (ENS) comprising administering an EGF receptor agonist, such as heparin-binding EGF (HB-EGF). These methods include reducing damage of ENS neurons in patient s suffering from an intestinal injury. In addition, the invention provides for increasing intestinal motility in a patient suffering from an intestinal injury comprising administering HB-EGF. The invention also provides for methods of inducing neurite growth within the ENS in a patient suffering from intestinal injury comprising administering HB-EGF.
