James R. Baker, Jr.,Xue-min Cheng,Abraham F. L. Van Der Spek,Baohua Mark Huang,Thommey P. Thomas
申请号:
US12570977
公开号:
US08889635B2
申请日:
2009.09.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer-linker conjugates of the present invention may further comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy.