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Cytoplasmic Tail Modifications to Boost Surface Expression and Immunogenicity of Envelope Glycoproteins
专利权人:
The Trustees of the University of Pennsylvania
发明人:
James A. Hoxie,Jordan Andrea Polacchini-Oliviera,Angela Conde,Drew Weissman
申请号:
US14417228
公开号:
US20150203540A1
申请日:
2013.07.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides compositions and methods for enhanced expression of a viral envelope protein. The invention provides a composition comprising a cytoplasmic tail modification to enhance surface expression of both HIV and non-HIV viral envelope proteins as wells as other membrane associated proteins resulting in increased immunogenicity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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