Edwin John Weeber,Stephanie Lynn Ciarlone,Dominic Paul DAgostino
申请号：
US15163194
公开号：
US09795580B2
申请日:
2016.05.24
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention concerns a method of treating Angelman Syndrome (AS) in a subject, comprising inducing ketosis in the subject by administering a therapeutically effective amount of a ketone ester, such as an R,S-1,3-butanediol acetoacetate ester, wherein administration of the ketone ester elevates the blood ketone level in the subject. Other aspects of the invention include a method of increasing cognitive function and/or motor function in a subject with AS and a method of decreasing seizures and increasing the latency to seize in a subject with AS.
