ELLIS, James Lamond,EVANS, Karen Anderson,FOX, Ryan Michael,MILLER, William Henry,SEEFELD, Mark Andrew
申请号：
SG11201703824Q
公开号：
SG11201703824QA
申请日:
2015.11.19
申请国别(地区):
SG
年份:
2017
代理人:
摘要：
The present invention relates to novel substituted bridged urea analog compounds of Formula (I) or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds, alone or in combination with other therapeutic agents, as Sirtuin Modulators useful for increasing lifespan of a cell, and for use in treating and/or preventing a wide variety of diseases and disorders, which include, but are not limited to, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity.
