Disclosed herein are novel uses of N-acetylcystein for the prophylaxis of preterm birth, still birth, or fetal death in a pregnant subject. According to embodiments of the present disclosure, the pregnant subject suffers from a bacterial infection, such as bacterial intrauterine infection, that leads to bacterial induced preterm birth, still birth, fetal death or fetal brain injury.本揭示內容是關於乙醯半胱胺酸的新穎用途,其可預防懷孕個體的早產、死產或死胎。依據本揭示內容的實施方式,該懷孕個體遭受一如細菌性子宮內感染等細菌感染,其會造成由細菌引發之早產、死產、死胎或胚胎腦損傷。