Crooke, Rosanne M.,Graham, Mark J.,Freier, Susan M.
申请号:
AU2017200277
公开号:
AU2017200277B2
申请日:
2017.01.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2017200277B220181018.pdf#####Abstract Provided within are methods, compounds, and compositions for reducing expression of Apolipoprotein (A) mRNA and protein in an animal. In certain embodiments, the compound is an antisense oligonucleotide inhibitor targeting Apo(A). Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions.