LONERGAN, DAVID,HOLME, KEVIN ROSS,ROWBOTTOM, MARTIN W.
申请号:
CA3036064
公开号:
CA3036064A1
申请日:
2017.09.06
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Described herein are crystalline forms of pharmaceutically acceptable salts of the lysyl oxidase-like 2 (LOXL2) inhibitor (3-(4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yloxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone. Also described are methods of making the LOXL2 inhibitor, pharmaceutical compositions and medicaments comprising the LOXL2 inhibitor, and methods of using the LOXL2 inhibitor in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.