David B Rozema,Jon A Wolff,James E Hagstrom,Kirk Ekena
申请号：
US14594229
公开号：
US20150273081A1
申请日:
2015.01.12
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention is directed to reversibly inactivated membrane active polymers useful for cellular delivery of compounds. Described are polyconjugate systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of multiple reversible linkages connecting component parts provides for physiologically responsive activity modulation.
