The compositions and methods described herein relate generally to therapeutic compositions containing Nerium species extracts, as well as to methods for treating diseases or disorders by administering the compositions, including compositions having a combination of Nerium species extract and glutathione. It further includes pharmaceutical compositions containing a combination of glutathione and a Nerium species extract. The compositions and methods disclosed may be useful for treating a variety of diseases or disorders including one or more cell-proliferative diseases or disorders, infections, and dementias.
