A method of radiation therapy planning and delivery is provided that includes introducing a demand metric, using a volumetric modulation arc therapy system, to select a spatially optimized and non-uniform set of station or control points to be used for intensity modulation, where the set of station or control points are uniform or non-uniform, and selecting a set of control points at different gantry angles, using the volumetric modulated arc therapy system, and using the demand metric to prioritize which station or control point receives intensity modulation, where the volumetric modulated arc therapy system is differentially boosted at selected angles by inserting additional segments to the station, where the inserted additional apertures dosimetrically boost desired regions in a planning target volume to improve planning target volume coverage in a single arc rotation while sparing sensitive structures.
