A system and method for planning a pathway through an anatomical luminalnetworkof a patient including memory storing a computer program configured to analyzeandmanipulate CT images, a processor configured to execute the computer program,and a display device configured to display a user interface of the computerprogram.The user interface includes a CT image window configured to display a slice ofCTimage data, a localizer window configured to display an image of at least onelung,the localizer window including a localizer configured to identify a locationof thedisplayed slice relative to the at least one lung, and a target selectionelementconfigured to select a target from a displayed slice of CT image data inresponse to auser input.