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SYNTHESIS OF BIOLOGICAL COMPOUNDS LABELED WITH THE ALPHA EMITTER Ac-225
专利权人:
发明人:
Alfred MORGENSTERN,Frank BRUCHERTSEIFER,Christos APOSTOLIDIS
申请号:
US14102865
公开号:
US20150157742A1
申请日:
2013.12.11
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method is described for producing a radioconjugate labeled with radionuclide Ac-225 comprising the step of chelating said radionuclide Ac-225 with a conjugated chelate compound in a chelation reaction mixture to obtain a radioconjugate labeled with Ac-225, wherein the pH of the chelation reaction mixture is comprised between 7.1 and 10, preferably between 8.0 and 9.5, more preferably about 9.0.
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