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Polyamine sulfonamides and uses thereof
专利权人:
University of Florida Research Foundation, Inc.;University of Florida Research Foundation;Torrey Pines Institute for Molecular Studies; Inc.
发明人:
Cogle, Christopher R.,Meacham, Amy M.,Sayeski, Peter P.,Giulianotti, Marcello A.,Houghten, Richard A.,Welmarker, Gregory S.
申请号:
AU2016348452
公开号:
AU2016348452A1
申请日:
2016.11.04
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Cancer is a disease for which there remains a great unmet medical need, and therefore the discovery and development of new antineoplastic agents is critically important. The present invention relates in part to new therapeutic compounds with antineoplastic activity. Provided herein are polyamine sulfonamides such as compounds of Formula (I), or pharmaceutically acceptable salts thereof, which may be used in the treatment and/or prevention of diseases such as cancer. Also provided herein are pharmaceutical compositions and kits comprising the inventive compounds. Furthermore, the present invention provides methods of treating and/or preventing diseases (
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