N1-(3,3,3-TRIFLUORO-2-HYDROXO-2-METHYLPROPIONYL)-PIPERIDINE DERIVATIVES AS INHIBITORS OF PYRUVATE DEHYDROGENASE KINASE

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专利权人:

MERCK PATENT GMBH

发明人:

Hans-Peter BUCHSTALLER

申请号：

US15105154

公开号：

US20160311798A1

申请日:

2014.11.19

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Compounds of the formula (I) in which R, R1 and R3 have the meanings indicated in claim 1, are inhibitors of pyruvate dehydrogenase kinase (PDHK), and can be employed, inter alia, for the treatment of diseases such as cancer.

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