DOUDNA, JENNIFER A.,BANFIELD, JILLIAN F.,BURSTEIN, DAVID,HARRINGTON, LUCAS BENJAMIN
申请号：
CA3038982
公开号：
CA3038982A1
申请日:
2017.09.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure provides CasY proteins, nucleic acids encoding the CasY proteins, and modified host cells comprising the CasY proteins and/or nucleic acids encoding same. CasY proteins are useful in a variety of applications, which are provided. The present disclosure provides CasY guide RNAs that bind to and provide sequence specificity to the CasY proteins, nucleic acids encoding the CasY guide RNAs, and modified host cells comprising the CasY guide RNAs and/or nucleic acids encoding same. CasY guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides methods of identifying a CRISPR RNA-guided endonuclease.
