Stabilization of fsh

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专利权人:

FERRING B.V.

发明人:

SJÖGREN HELEN ULRIKA,BAGGER HEIDI LOUISE

申请号：

NZ60636611

公开号：

NZ606366A

申请日:

2011.07.28

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

606366 Disclosed is the use of salts comprising pharmaceutically acceptable alkali metal cations to limit the tendency of FSH to dissociate in a liquid FSH formulation, wherein the salt is selected from the group consisting of pharmaceutically acceptable Na+ salts and K+ salts, or a combination thereof. Disclosed is a method for limiting the tendency of FSH to dissociate in a liquid FSH formulation wherein the method comprises the step of an addition of salts comprising pharmaceutically acceptable alkali metal cations to said formulation, wherein said salts are selected from the group consisting of pharmaceutically acceptable Na+ salts and K+-salts, or a combination thereof.

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