PEREZ GARCIA, JUAN BAUSTISTA,CARRERA CARRERA, FRANCESC,GARCIA MARTIN, DIGNA JOSE,BOIX BERNARDINI, MARIA CARMEN
申请号:
MYPI 2011004300
公开号:
MY155140A
申请日:
2010.03.11
申请国别(地区):
MY
年份:
2015
代理人:
摘要:
THE PRESENT INVENTION IS DIRECTED TO NOVEL WATER-SOLUBLE PHARMACEUTICALLY ACCEPTABLE, CRYSTALLINE ADDITION SALTS OF (I) AN AMINE CONTAINING ONE OR MORE HYDROXYL AND/OR CARBOXYLIC GROUPS WITH (II) AMINO NICOTINIC ACID DERIVATIVES OF FORMULA (I) WHEREIN Rᵃ, Rᵇ, Rᶜ AND Rᵈ INDEPENDENTLY REPRESENT GROUPS SELECTED FROM HYDROGEN ATOMS, HALOGEN ATOMS, C₁-₄ ALKYL GROUPS WHICH MAY BE OPTIONALLY SUBSTITUTED BY 1, 2 OR 3 SUBSTITUENTS SELECTED FROM HALOGEN ATOMS AND HYDROXY GROUPS, AND C₁-₄ ALKOXY GROUPS WHICH MAY BE OPTIONALLY SUBTITUTED BY 1, 2 OR 3 SUBSTITUENTS SELECTED FROM HALOGEN ATOMS AND HYDROXY GROUPS, AND PHARMACEUTICALLY ACCEPTABLE SOLVATES THEREOF.