Roland K. Strong,Colin Correnti,Leonidas Stamatatos,Andrew McGuire
申请号：
US16430172
公开号：
US20190321461A1
申请日:
2019.06.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Engineered and multimerized human immunodeficiency virus (HIV) envelope glycoproteins are described. The envelope glycoproteins can be multimerized using a heptamerization domain such as a C4b binding protein multimerization domain or a ferritin fusion. The engineered and multimerized envelope glycoproteins can derived from glycoprotein 120 (gp120) and can used as an HIV vaccine.
