Hugh Y. RIENHOFF, Jr.,John M. MCCALL,Michael CLARE,Cassandra CELATKA,Amy E. TAPPER
申请号：
US15952073
公开号：
US20180312474A1
申请日:
2018.04.12
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.
