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COMPOSITIONS, USES, AND PREPARATION OF PLATELET LYSATES
专利权人:
EMORY UNIVERSITY;CHILDREN'S HEALTHCARE OF ATLANTA, INC.
发明人:
Ian B. Copland,Jacques Galipeau
申请号:
US15607123
公开号:
US20170304365A1
申请日:
2017.05.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In certain embodiments, this disclosure describes compositions comprising platelet lysates depleted of fibrinogen. In a further embodiment, the composition further comprises a cell culture medium component. This disclosure also provides a method for preparing the composition, comprising the steps of (a) lysing platelets providing a lysate; (b) removing cell debris; and (c) depleting fibrinogen by forming a removable mass by adding a metal salt such as calcium chloride. Furthermore, the disclosure also describes the product produced using said method.
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