Marie Baccara-Dinet,Corinne Hanotin,Laurence Bessac,Umesh Chaudhari,Robert C. Pordy,William J. Sasiela,Daniel A. Schwemmer Gipe
申请号：
US16707492
公开号：
US20200216565A1
申请日:
2019.12.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides methods for treating hypercholesterolemia. The methods of the present invention comprise administering to patients with heterozygous familial hypercholesterolemia a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. The methods of the present invention are useful for treating patients with heterozygous familial hypercholesterolemia who are not adequately controlled by maximum tolerated dose statin therapy with or without other lipid lowering therapy.
