Clifford J. Holmes;Leo Martis;Rahul Tandon;Sujatha Karoor;John Kenneth Leypoldt;Catherine M. Hoff
发明人:
John Kenneth Leypoldt,Clifford J. Holmes,Sujatha Karoor,Catherine M. Hoff,Leo Martis,Rahul Tandon
申请号：
US13419701
公开号：
US20120238525A1
申请日:
2012.03.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Peritoneal dialysis solutions including a glucose polymer and methods of using the dialysis solutions are disclosed herein. In a general embodiment, the peritoneal dialysis solution includes a glucose polymer in an amount to provide an increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed compared to conventional dialysis solutions containing icodextrin as the active pharmaceutical ingredient. The increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed is obtained by providing specific combinations of weight-average molecular weight, polydispersity index and concentration of the glucose polymer in the dialysis solution.
