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Degradable removable implant for the sustained release of an active compound
专利权人:
JANSSEN R&D IRELAND
发明人:
KRAUS GUENTER,SCHACHTER DEBORAH M.,CHUN IKSOO,ZHANG QIANG,BAERT LIEVEN ELVIRE COLETTE
申请号:
NZ60015610
公开号:
NZ600156A
申请日:
2010.12.20
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is a degradable, removable, pharmaceutical subcutaneous implant for the sustained release of one or more active agents in a subject, wherein the pharmaceutical implant is composed of a tube comprising an outer wall made of a degradable polymer completely surrounding a cavity, wherein the outer wall has a plurality of openings and wherein the cavity contains one or more sets of micro-particles, which micro-particles contain the one or more active agents (such as rilpivirine), wherein the microparticles are fabricated from a biocompatible, biodegradable polymer (such as copolymers of lactide and glycolide), wherein the size of the microparticles is selected such that the majority of the microparticles cannot pass through the openings, and wherein the degradation rate of the polymer that composes the tube is slower than the rate of degradation of the microparticles.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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