A method for the production and filling of an application package for a liquid pharmaceutical product. A thermoforming film of thermoplastics laminated together is heated in order to plasticize the film at least in partial areas. Plasticized areas are thermoformed in a mold in order to form a chamber for the liquid pharmaceutical product and a tube-shaped application duct opening into this chamber, with the chamber and duct being enclosed by a non-thermoformed, essentially flat bonding area of the film. The liquid pharmaceutical product is filled into the chamber. The chamber and the application duct are sealed by covering the thermoformed and filled thermoforming film with an essentially flat covering film that is bonded to the bonding area of the thermoforming film enclosing the chamber and the application duct. The thermoforming film is pressed by a forming die during thermoforming into the mold in at least a partial area of the application duct.
