BECK, Hilary Plake,WILLIAMS, David K.,GUO, Weiwei,JAEN, Juan Carlos,OSIPOV, Maksim,POWERS, Jay Patrick,REILLY, Maureen Kay,SHUNATONA, Hunter Paul,WALKER, James Ross,ZIBINSKY, Mikhail,BALOG,James Aaron
申请号：
USUS2015/059271
公开号：
WO2016/073738A2
申请日:
2015.11.05
申请国别(地区):
WO
年份:
2016
代理人:
摘要：
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune -related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.Linvention concerne des composés qui assurent la modulation de lenzyme oxydo-réductase indoleamine 2,3-dioxygénase, ainsi que des compositions contenant ces composés. Linvention concerne également lutilisation de tels composés et compositions dans le traitement et/ou la prévention dun ensemble varié de maladies, troubles et affections, y compris de troubles liés au cancer et à limmunité, à médiation par lindoleamine 2,3-dioxygénase.
