INDUSTRY-ACADEMIC COOPERATION FOUNDATION; YONSEI UNIVERSITY
发明人:
YOON, SANG SUN,윤상선,PARK, YONG JIN,박용진,BARI WASIMUL,바리 와시멀
申请号:
KR1020110140261
公开号:
KR1020130072720A
申请日:
2011.12.22
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: A method for producing cholera toxin using trimethylamine N-oxide (TMAO) is provided to simply and efficiently produce cholera toxin.CONSTITUTION: A method for increasing the amount of cholera toxin comprises the step of culturing Vibrio cholerae in a medium containing an electron receptor under an anaerobic condition. The vibrio cholerae is O1 serotype which is one of O395, C6706, 569B, and N16961. A method for producing cholera toxin comprises the steps of: culturing the Vibrio cholerae in the medium under an anaerobic condition and colleting cholera toxin.COPYRIGHT KIPO 2013본 발명은 TMAO를 이용한 콜레라 톡신의 생산 방법에 관한 발명으로, 본 발명에 의할 경우 콜레라 톡신을 간단하면서도 효율적으로 생산할 수 있다.