Gastrointestinal bypass devices are described. In one embodiment, a gastrointestinal bypass device includes a liner having a proximal portion configured to be at least partially positioned in the esophagus and a distal portion configured to be at least partially positioned in the intestine. The gastrointestinal bypass device also includes a framework coupled to the proximal portion of the liner and a tissue ingrowth area formed at the proximal portion of the liner.