Methods for treating glioblastoma in a subject comprising administering to the subject an inhibitor of a Src family kinase. Methods for inhibiting the migration of a glial cell comprising contacting the glial cell with an inhibitor of a Src family kinase or reducing the expression of a Src family kinase in the glial cell. Methods for reducing or inhibiting tumor formation in a subject comprising administering to the subject an inhibitor of a Src family kinase or administering an oligonucleotide or a gene editing system that reduces the expression of a Src family kinase within a cell. Ex vivo co-culture systems comprising a Dorsal Root Ganglion (DRG) axon-oligodendrocyte and a gliomal cell. Methods for identifying an inhibitor of glial cell migration or movement. Methods for treating glioblastoma and for isolating pseudopodia of a gliomal cell and for identifying RNA present therein.
