A method and systems for treating chronic total occlusions, particularly thosethat are difficult to treat, is disclosed. In this approach, recanalizing theCTO is achieved using a combined antegrade and retrograde approach. Theproximal end of the occlusion is penetrated using an antegrade wire, using atraditional approach. Using collateral vessels, the distal end of theocclusion is crossed in a retrograde fashion and by appropriately maneuveringeach member, a continuous channel is created. Additional elements such ascapture devices, dilators and injection catheters are also disclosed.