Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-b]pyrazin-2(1h)-one, a solid form thereof and methods of their use
XU JEAN,CONNOLLY TERRENCE JOSEPH,KLOPFER KEVIN JOSEPH,LEONG WILLIAM WEI-HWA,MENON ANIL,MIKLOS AMANDA NICOLE,COHEN BENJAMIN,LEE THOMAS,BOERSEN NATHAN,KREILEIN MATTHEW MICHAEL,LI YING,HUI HO-WAH,GAMBOA
申请号：
NZ71112312
公开号：
NZ711123A
申请日:
2012.11.30
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed is a solid form of the compound 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one represented by the structural formula shown herein, having an X-ray powder diffraction pattern with one or more peaks expressed in two-theta at approximately 8.3, 8.8, 13.2, 16.5, 17.7, 18.2, 21.7 or 26.5 degrees and having XRPD peaks at approximately 8.3, 13.2, 18.2 or 21.7 degrees, and a DSC thermogram with an endotherm at a peak temperature of about 199 ºC.
