An aspiration system is disclosed for removing body liquid (e.g. urine or a secretion) discharged by the human body. The aspiration system comprises a body interface device with a liquid sensor, and an aspiration unit coupled to the body interface device. The liquid sensor comprises a temperature sensor and/or a resistance bridge. The aspiration unit includes: a vacuum chamber; a pump for pre-charging the vacuum chamber with a vacuum; a valve coupled between the vacuum chamber and the body interface device; and a control circuit for controlling the valve to apply aspiration suction from the vacuum chamber to the body interface device in response to detection of body liquid at the liquid sensor.