Manfred Franke,Stephen B. Ruble,David J. Ternes,Juan Gabriel Hincapie Ordonez,Jason J. Hamann
申请号:
US14557707
公开号:
US09370659B2
申请日:
2014.12.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
An example of a method embodiment may deliver intermittent neural stimulation (INS) therapy to an autonomic neural target of a patient. The INS therapy includes neural stimulation (NS) ON times alternating with NS OFF times, and includes at least one NS burst of NS pulses during each of the NS ON times. For a given NS OFF time and subsequent NS ON time, delivering INS therapy may include monitoring a plurality of cardiac cycles during the NS OFF time, using the monitored plurality of cardiac cycles to predict cardiac event timing during the subsequent NS ON time, and controlling delivery of the INS therapy using the predicted cardiac event timing to time NS burst delivery of at least one NS burst for the subsequent NS ON time based on the predicted cardiac event timing.