The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.本發明係有關於一種以吡唑基為基礎之羧醯胺化合物,其可用為ICRAC之抑制劑,用來製備含有上述這些化合物之醫藥組合物,以及用來治療及/或預防疾病或失調,尤其是發炎性之疾病或失調。