Harald S. Hansen,Thi Ai Diep,Jens Juul Holst,Mette Marie Rosenkilde,Niels Wellner Andersen
申请号:
US13380086
公开号:
US20120128770A1
申请日:
2010.06.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to 1 or 2 C16-C18 acyl glycerol based compounds which are capable of activating G-protein coupled receptor 119 and thereby stimulate GLP-1 release. Compounds of the present invention are useful in the prophylaxis and/or treatment of metabolic disorders and complications thereof, such as, type 2 diabetes mellitus (T2DM), obesity, insulin resistance, and cardiovascular disease.