Factor VIII B cell epitope variants having reduced immunogenicity

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专利权人:

发明人:

申请号：

EP13191686.8

公开号：

EP2742949A1

申请日:

2010.11.15

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Provided herein are methods and compositions for preventing or reducing an initial immune response to factor VIII in patients suffering from hemophilia A, and for reducing the intensity of the immune response in patients having pre-formed inhibitor antibodies against factor VIII.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/