CHINH TRAN,DOUGLAS MURPHY,JUSTIN T. ERNST,MIKE SHAGHAFI,PAUL, A. SPRENGELER,SIEGFRIED H. REICH,STEPHEN E. WEBBER
申请号：
BR112018008714
公开号：
BR112018008714A2
申请日:
2016.10.28
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The present invention provides compound or its stereoisomer of formula (I), the synthesizing of tautomer or pharmaceutically acceptable salt, pharmaceutically acceptable preparation and purposes.For the compound of Formulas I, A1、A2、A3、A4、A5、W1、Y、R1、R2、R3、R4、R5、R6a、R6b、R7、R8、R8a、R8b、R9、R9a、R9bAnd R10And the definition of subscript " n " is as used in the description.The compound of formula I of the present invention is the inhibitor of Mnk and can be used for many treatment uses, including but not limited to treats inflammation and various cancers.
