Sumitra Rajagopalan,Wilms Baille,Piotr Kujawa,Christopher A. Zook,Rebecca R. Quesnell,Dennis L. Huczek,Stephen L. Secreast,Laibin Luo,Tammy A. Sanders
申请号：
US15341028
公开号：
US10064870B2
申请日:
2016.11.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure relates generally to sol-gel polymer composites that comprise chitosan, a hydrophilic polymer, a gelation agent, and optional additional ingredients in a suitable medium. Advantageously, the sol-gel polymer composite can form a durable seal or strong solid in response to one or more physiological stimulus. The disclosure further relates to medical and veterinary uses of the composite, particularly, methods and delivery systems for reducing or preventing the incidence of a mammary disorder in a dairy animal. More particularly, the disclosure includes methods and sol-gel polymer composite compositions for creating a physical barrier on the teat surface or in the teat canal or cistern of a non-human animal for prophylactic treatment of mammary disorders such as mastitis wherein the sol-gel polymer creates a seal in response to one or more physiological stimulus.
